MK-677, also known as Ibutamoren, or Nutrobal, is a growth hormone secretagogue. Although it’s commonly referred to as a SARM, most of its action centers on stimulating the pituitary hormone to express Human Growth Hormone (HGH).
MK-677 Ibutamoren acts by increasing human growth hormone levels and IGF-1 (insulin-like growth factor 1). Ibutamoren also mimics the action of ghrelin, a normally occurring hormone responsible for stimulating your appetite.
Ibutamoren MK677 Overview
Ibutamoren is specially designed to stimulate the pituitary gland, increasing its own growth hormone production up to 3 times. This is a very desirable effect because taking 20mg would be equal to the increase of 2iu (units) you would expect from injecting a real growth hormone like Pfizer Genotropin.
Ibutamoren (MK-677) is part of SARMs (Selective Androgen Receptor Modulators) and mimics the action of the most expensive component in hormone therapy, namely growth hormone . Unlike ordinary injectable growth hormone, Ibutamoren indirectly stimulates pituitary gland the body’s to work at maximum speed. In this way, the body only produces a huge amount of growth hormone which provides a bunch of positives for the consumer without side effects.
According to research, MK-677 improves physical condition, helps build muscle mass during exercise, burns fat and improves metabolism along with energy levels. With prolonged use (6-12 months) Ibutamoren has rejuvenating effects on consumers, removes wrinkles and makes the skin smoother. Other positive properties of this SARM are the elimination of fatigue, depression and hair growth.
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Research studies and human trials
MK-677 was tested on healthy males over 60 y/o. The result was an increase in muscle mass in strength. Proof of lean body mass strength and increase showed in 40k counting, urinary creatinine excretion, and isokinetic dynamometry.
Nutrobal also shows promise in bone health as it helped improve recovery from a hip fracture. Elderly patients who participated in the study showed improved gait speed, lesser fall incidents, and mean stair climbing.
Research of MK-677 on obese men aged 18-50 manifested increased GH and IGF-1 levels. There was also an increase in energy expenditure, fat-free mass, as well as basal metabolic rate.
MK-677 studies also resulted in improved sleep quality in both young and older adults. Regulated doses administered in two 14-day cycles separated in 14 days showed a 20% increase in REM sleep.
MK-677 Side Effects
There’s a need for further research to determine the safety and efficacy of MK-677, especially when it comes to prolonged use.
If there’s a common side effect associated with MK-677 that would be muscle pain and an almost uncontrollable appetite due to increased levels of ghrelin. Others showed higher fasting blood glucose, indicating lowered insulin sensitivity.
Studies regarding recovery from hip fracture were also cut short because participants were showing unstable blood glucose, increased blood pressure, and risk of congestive heart failure. This indicates that MK-677 is not advised for elderly patients.
MK-677 is also contraindicated for research with cancer patients or patients with a family history of cancer, as well as TH 1 dominants due to its anabolic nature.
Our MK-677 and all our biotech SARMs passed a rigorous third-party analysis from a US lab. Every batch of MK-677 we receive requires a third-party analysis run for authenticity. Nutrobal is legal for sale in the United States, European Union, as well as parts of Asia, with the provision that it’s strictly for use in research and lab studies.
These products should not be used or labeled as a drug, pesticide or agricultural products, additives, or household chemical. Administration of MK-677 on humans and animals is against the law. The product should only be handled by qualified and licensed professionals and researchers. MK-677 is strictly for research purposes only.
Who is Ibutamoren MK677 suitable for?
As the main function of MK677 is to increase the production of growth hormone, it is suitable for both men and women. It can be used for weight gain or weight loss, depending on the combination of SARMs you choose and the diet you follow.
In short Ibutamoren:
- It melts fat and promotes muscle growth
- Increases energy levels during the day and restores the skin
- Enhances the action of other SARMs with which it is combined
Do we need to do post-cycle therapy with SARMs??
At the end of the cycle comes the most important moment, rehabilitation therapy which helps the body return to its normal rhythm, but is this necessary for SARMs?
In the normal therapeutic process in which small doses of SARMc are used for the period from 6 to 12 months (doses from 1 to 3 mg.). But the difference with us is that in order to achieve our goals related to muscle growth faster, we use higher doses and accordingly we have several options for therapy after a cycle. –
“SARMs do not suppress testosterone, why is my therapy after a cycle?”
Yes, therapeutic doses do not suppress testosterone function in any way, but when we take larger doses for rapid muscle and strength growth, something else happens.
The SARM supplements (with the exception of Cardarin, Stenabolic and Ibutamoren) occupies almost all androgen receptors, which in turn prevents your own hormone testosterone from binding to them and therefore the need (from the point of view of the body not using it during SARMs). ) decreases.
This can lead to lower levels of testosterone production because it cannot be used optimally at this time due to a lack of free androgen receptors.
For this reason, some people do not experience any side effects . They have more androgen receptors, which allows testosterone to interact normally with them.