Taking CBD and THC Together: Here is What you Need to Know

Vaping CBD: The Top Pros and Cons

Cannabis plants produced a vast array of phytochemicals from terpenes to terpenoids and others. Two of the most well-researched and popular phytocannabinoid compounds are cannabidiol and tetrahydrocannabinol. In some cases, it may be beneficial to take CBD and THC separately, depending on how you feel.

Studies suggest it may be more beneficial to treat patients when CBD and THC are combined, along with other ingredients in cannabis. The entourage effect is a result of interactions between the various compounds within the cannabis flower.

How do CBD and THC interact? Is it beneficial or not? Would you like to know how?

In this guide, you will see the effects and benefits of CBD and THC together. Do they work together? But How?

In case you are worried about CBD and THC, then read all of this article.

What are CBD and THC?

The hemp plant contains cannabidiol, a non-psychotropic component of the cannabis family. CBD has been reported to have an alerting effect on many patients. In other words, it doesn’t provide the high feeling associated with cannabis. Thus, it’s important to avoid using it at night in high amounts.

A cannabis plant’s psychoactive ingredient is THC. Consequently, it generates the high sensation that comes with cannabis. By ingesting THC, dopamine is released into the brain. Dopamine produces a sense of wellbeing and euphoria when it is released. In addition, it relaxes the user.

What is CBD with THC Called?

There is extensive research that suggests that cannabis’s cannabinoids and terpenoids interact with the brain’s receptors. It has been called “the entourage effect.” It is possible that taking THC and CBD together makes them more effective than either alone due to the entourage effect.

An entourage effect occurs when terpenes, THC, or CBD interact, producing a synergistic effect. The result is a more powerful effect than what either of them would have created on their own.

Do CBD and THC work together?

THC and CBD have important effects on each other when taken together from a therapeutic perspective. CBD extends the effects of THC therapy when it is taken along with THC by inhibiting the breaking down of THC in the liver. Inhibition of the THC breakdown prolongs its effects.

Consumption of CBD along with THC may reduce the psychoactivity most patients normally experience from THC.

Researchers in San Francisco at California Pacific Medical Center demonstrate that using specific amounts of THC and CBD can eliminate tumors in breasts and brains.

How Does CBD Work with THC?

THC and CBD mimic the natural endocannabinoids produced by the body. As a result, they have a number of biological effects on humans. Among other functions, these endocannabinoids maintain a balance in appetite, the immune system, sleep, and pain. As a result of this imbalance, the body becomes stressed.

The endocannabinoid system steps in to fix the problem. THC and CBD resemble natural endocannabinoids. CBD and THC both modulate the endocannabinoid system, thereby alleviating inflammation, pain, and several other conditions. In this way, they enable your body to cope with a crisis while restoring balance after trauma if the body’s endocannabinoids cannot do it on their own.

Why Should You Add THC in Your CBD?

You may also want to mix a small amount of THC with your CBD because CBD is more beneficial when consumed together with THC.

There is evidence that cannabis compounds work together in synergistic ways to produce health benefits. In other words, although cannabis alone is powerful, it can have different effects when mixed with THC. It is also possible to derive therapeutic effects from CBD when a little THC is present.

While some people have tried CBD creams to no avail, the CBD full spectrum cream has been developed for the purpose. In full-spectrum, CBD has a very small amount of THC, 0.3%. Furthermore, it contains THC, which contributes to a sense of relief and relaxation.

Benefits of CBD and THC together

It is now possible to consume cannabis in ways other than through its THC effects. Today, people want both cannabinoids in their weed – they want the combination of health benefits.

When taken CBD and THC together, the benefits of both cannabinoids are greatest, and you can achieve more complex results.

Preclinical research has shown that combining THC with CBD can produce better results t in many forms.

In a study conducted on patients with glioblastoma, a type of brain cancer, THC and CBD combined suppress cell growth far better than the two cannabinoids alone.

Animal models have demonstrated that CBD is more effective in breast cancer. With a 4% CBD dosage combined with THC, CBD can reduce many of the psychoactive effects experienced by patients when THC is present, although more research is needed.

Side Effects of CBD with THC

The effects of CBD are well tolerated at even high doses. If you use CBD or THC together with other medications, there may be side effects resulting from interactions.

The following side effects may occur:

  • Dry mouth
  • Red eyes
  • Anxiety
  • Increased heart rate
  • Fatigue
  • Weight loss
  • Dizziness
  • Memory loss
  • Diarrhea

Psychoactive compounds are known to have these side effects. Both compounds are not deadly.

In contrast, excessive THC use may have negative mental health effects over the long run. In terms of schizophrenia and cannabis, there is no conclusive evidence that smoking cannabis causes these disorders. Despite this, large doses of THC may have adverse effects on adolescents.

How to Add THC in CBD?/ Tips for adding THC in CBD

Cannabis affects everyone differently, even if THC and CBD can work well together. Everyone’s body responds to different dosages and ratios. But if you want to start CBD and THC together, then you must consult your doctor.

If you suffer from chronic diseases such as cancer, HIV/Aids, and many others, your doctor may suggest a better idea to take CBD and THC together with other medications.

It is likely that the amount of THC in cannabis-based medicines will vary among those who take it for nausea relief versus those who take it for muscle pain.

As a beginner, start with only 5mg of THC and increase the dose if you do not feel well.

Further, it is important to note that marijuana is illegal both federally and state-wise. If you are considering using THC-infused products, it is important to familiarize yourself with the laws in your area.

Ways of Taking CBD and THC together?

CBD and THC can be taken in many ways, such as

  • Food products
  • Gummies
  • Capsule
  • Tinctures
  • Vapes
  • Topicals

CDC recommends people avoid vape products that contain THC. In conjunction with THC, CBD vaping can cause serious side effects. When using a vaping product, monitor yourself closely.

You may experience cold in the form of cough, nausea, chest pain, exhaustion, fatigue, and weight loss. In case of any of these symptoms, please contact your doctor.

Does CBD Counteract THC?

In reality, CBD has shown inconsistent results when it comes to blocking the effects of THC. It has been shown that CBD could improve the effects of THC in some cases and that it could also worsen them in other cases. It is because CBD and THC interact in multiple ways.

The first is by modulating the effect of another molecule through a pharmacokinetic mechanism. A large part of CBD’s effect is caused by inhibiting CYP2C9, which creates a higher blood concentration of THC. For the metabolism of THC, this enzyme is essential. Furthermore, administered CBD before THC, rats, and mice exhibited higher blood and brain levels of the psychoactive compound.

It is also possible to modulate the effects of another molecule directly through the effects of direct pharmacodynamics, which occurs when molecules bind to the same receptors.

The CB1 receptor’s activity is decreased by a negative allosteric modulator such as CBD.


Do you really need to take CBD and THC together?

Suppose you are already taking medication for chronic diseases such as cancer, HIV/Aids, glioblastoma, and many others. In that case, you must take to avoid CBD and THC together because they may interact with other medications.

Is CBD still beneficial without THC?

According to an entourage effect, CBD works better when you take CBD and THC together. Even without THC, CBD oil is still effective. According to some research, CBD may still be able to produce therapeutic effects on its own.

Do CBD and THC Bind to the Same Receptor?

The human body’s endocannabinoid system contains cannabinoids like THC and CBD, which bind to these receptors. Several bodily functions, including immunity and mood, are regulated by the endocannabinoid system, which was found in the early 1990s.

Is CBD oil with THC legal?

CBD is legal only on the federal level regarding the low amount of THC with less than 0.3%. But this type of CBD is still illegal in some states. The federal government declares marijuana-derived CBD products illegal, but some states allow them.


Medicinal cannabis contains both CBD and THC, which are used to increase its therapeutic effects on the body. Each has its own unique benefits and side effects for medicinal purposes.

When CBD and THC are combined, scientific research proves that THC side effects are significantly reduced when taken alone.

Researchers and clinical trials have shown that taking CBD and THC together can reduce cancer-related symptoms and reduce pain.

If you have a specific medical condition, your doctor can help you to select the appropriate ratio of CBD and THC.

For more information check out New Phase Blends.

Written by Frederick Jace

A passionate Blogger and a Full time Tech writer. SEO and Content Writer Expert since 2015.

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